Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1244995 | Talanta | 2007 | 6 Pages |
Abstract
A simple, sensitive and selective flow injection-chemiluminescence method for the determination of sulfadiazine in compound naristillae has been investigated. It is based upon the chemilimunescence reaction of sulfadiazine, formaldehyde and potassium permanganate in polyphosphate acid medium. The optimum conditions for the chemiluminescence emission were investigated. Under the optimum conditions, the linear range for the determination of sulfadiazine was 8.0Â ÃÂ 10â7 to 2.0Â ÃÂ 10â4Â mol/L with a detection limit of 2.0Â ÃÂ 10â7Â mol/L calculated as proposed by IUPAC and a relative standard deviation of 2.53% for 11 solutions of 5.0Â ÃÂ 10â5Â mol/L sulfadiazine on the same day. It was also found that the coexisting ephedrine hydrochloride did not interfere with this determination. This led to the successful application of the proposed method for the direct and selective determination of sulfadiazine in compound naristillae.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Haiyan Liu, Juanjuan Ren, Yuhong Hao, Pingang He, Yuzhi Fang,