Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1245200 | Talanta | 2007 | 7 Pages |
Abstract
In this paper, the synthesis of a cyclic hexapeptide molecule was presented and evaluated for the enantiomer separation of a series of dansyl amino and arylalkanoic acids using high performance liquid chromatography (HPLC). It was clearly vizualized that this chiral selector allowed the separation of a great number of enantiomer pairs. The influences of the size and the hydrogen bonding donor (HBD) parameter of the organic modifier (OM) (THF (HBD = 0.00), propan-2-ol (HBD = 0.33), methanol (HBD = 0.43)) added in the mobile phase were also investigated on both the enantiomer-chiral selector association and enantioseparation.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Claire André, Mireille Thomassin, Arunalyat Umrayami, Lhassane Ismaili, Bernard Refouvelet, Yves-Claude Guillaume,