Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1245579 | Talanta | 2008 | 9 Pages |
Abstract
In this paper we describe the strategy used in the development and validation of a near-infrared diffuse reflectance spectroscopy method for identification and quantification of ranitidine in pharmaceutical products (granulates, cores and coated tablets) at-line, with a fiber optic probe. This method was developed in a pharmaceutical industry for routine application, to replace reference methods and was submitted and approved to the National Medicine Regulatory Agency (Infarmed). We consider that this is the first step of a broader parametric release approach to pharmaceutical products.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Sílvia S. Rosa, Pedro A. Barata, José M. Martins, José C. Menezes,