Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1245679 | Talanta | 2006 | 6 Pages |
Abstract
Analytical procedure for the determination of toxicologically relevant arsenic (the sum of arsenite, arsenate, monomethylarsonate and dimethylarsinate) in urine by flow injection hydride generation and collection of generated inorganic and methylated hydrides on an integrated platform of a transverse-heated graphite atomizer for electrothermal atomic absorption spectrometric determination (ETAAS) is elaborated. Platforms are pre-treated with 2.7 μmol of zirconium and then with 0.10 μmol of iridium which serve both as an efficient hydride sequestration medium and permanent chemical modifier. Arsine, monomethylarsine and dimethylarsine are generated from diluted urine samples (10-25-fold) in the presence of 50 mmol Lâ1 hydrochloric acid and 70 mmol Lâ1l-cysteine. Collection, pyrolysis and atomization temperatures are 450, 500, 2100 and 2150 °C, respectively. The characteristic mass, characteristic concentration and limit of detection (3Ï) are 39 pg, 0.078 μg Lâ1 and 0.038 μg Lâ1 As, respectively. The limits of detection in urine are ca. 0.4 and 1 μg Lâ1 with 10- and 25-fold dilutions. The sample throughput rate is 25 hâ1. Applications to several urine CRMs are given.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Panayot K. Petrov, Ivan Serafimovski, Trajce Stafilov, Dimiter L. Tsalev,