Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1245796 | Talanta | 2006 | 4 Pages |
Abstract
A flow-injection turbidimetric procedure exploiting merging zones is proposed for determining homatropine methylbromide (HMB) in pharmaceutical preparations. The determination is based on the precipitation reaction of homatropine methylbromide with silicotungstic acid in acidic medium to form a precipitate, which was measured at 410 nm. The analytical curve was linear in the HMB concentration range from 8.1 Ã 10â5 to 2.2 Ã 10â4 mol lâ1, with a detection limit of 5.0 Ã 10â6 mol lâ1. The recoveries ranged from 96 to 103%, the sampling frequency was 70 determinations per hour and relative standard deviations were less than 1.5% (n = 10). The results obtained for commercial formulations using the FIA procedure were in good agreement with those obtained by using a comparative method.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Larissa S. Canaes, Oldair D. Leite, Orlando Fatibello-Filho,