| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1246560 | Talanta | 2006 | 6 Pages |
Abstract
The response characteristics of various carbon substrates towards the direct oxidative measurement of urate and other key purine biomarkers have been compared. A novel carbon fibre laminate assembly has been proposed as an alternative substrate for the preparation of disposable sensing strips. The fabrication method is generic and readily transferable to a number of sensor applications. Its performance in the determination of urate within biofluids (serum and plasma) has been critically assessed. An inter-laboratory pilot study demonstrated the bioanalytical efficacy of the approach with the responses validated through comparison with the standard colorimetric (uricase/peroxidase) assay.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Jodi S.N. Dutt, Callum Livingstone, Marco F. Cardosi, Shelley J. Wilkins, James Davis,