Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1247789 | TrAC Trends in Analytical Chemistry | 2015 | 18 Pages |
Abstract
Many physiological disorders, including Parkinson's, Alzheimer's and schizophrenia, are associated with variations in the biological levels of neurotransmitters and affect, e.g., learning, sleeping, memory, consciousness, and mood. Real-time, ultrasensitive and accurate detection of neurotransmitter levels in biological fluids not only improves the quality of a patient's life but also can reduce the cost of treatment. Advanced materials can offer remarkable opportunities in the design of bioimaging methods. With advanced materials, hopes of introducing “molecule-sensitive” methods with in-situ scientific instrumentation capability increase. This review aims to highlight recent advancements in materials used for detection of important neurotransmitters and focuses on the analytical features of the optical-based methods available.
Keywords
LCGCNTSTGANIRcpsSERSSAMsASPGSHHRPMPNNanoclustersNTANCSGCEDBAECLQDsCNPsRRSMBALucigeninChOxDTSSPLACPBSRSD5-HTMWCNTsPEIBSAPMAγ-amino butyric acidAdenosine TriphosphateATPAspartic acidAscorbic acidbovine serum albuminAChAChEAcetylcholineacetyl cholinesteraseSchizophrenia4-Mercaptophenylboronic acidThioglycolic acidUric acidnitrilotriacetic acidPolymethacrylic acidglutamic acidglassy carbon electrodeElectrochemiluminescencerelative standard deviationEpinephrineIndium tin oxideGraphene oxideITOAlzheimer's diseaseParkinson's diseaseOptical biosensingDetectionBioimagingSelf-assembled monolayersLOD یا Limit of detectionOptical sensingCNSDopamineSerotonincentral nervous systemSurface-enhanced Raman spectroscopyLaccaseNear infraredBiological fluidlimit of detectionphosphate buffer solutionAdvanced materialCarbon nanodotsMultiwalled carbon nanotubesMesoporous silica nanoparticleCarbon nanoparticlesCarbon nanotubesquantum dotsnorepinephrineNEPPAMAMHorseradish peroxidaseResonance Rayleigh scatteringPolyamidoaminepolyethylene glycolpolyethyleneimineConjugated polymersPEGNeurotransmitterCdScholine oxidaseGABAGluGlutathione
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Jafar Soleymani,