Mass-spectrometry-based metabolomics analysis for foodomics

•The current state of MS-based metabolic profiling methods in food science.•Multi-disciplinary approaches needed to link food and diet with health and disease.•Foodomics characterizes food composition, quality assurance, nutrition and health.•Challenges in developing metabolomics approaches for foodomics applications.

Mass spectrometry (MS) has gained popularity in metabolomics due to its unparalleled sensitivity and specificity, high resolution and wide dynamic range. MS-based metabolomics techniques have driven the emergence of a new omics sub-discipline – foodomics. In this review, we present the current state of MS-based metabolomics and typical applications in food science related to food composition, food safety, quality, nutrition and health.