Characterization of biopharmaceuticals by NMR spectroscopy

•NMR offers advantages over other techniques for characterizing biopharmaceuticals.•NMR technology is faster, more automated and more sensitive than ever before.•NMR is used in discovery, characterization and assessment of biopharmaceuticals.•NMR is used in formulation, production and quality control of biopharmaceuticals.

Recent improvements in nuclear magnetic resonance (NMR) – automation, sensitivity, resolution, pulse-sequence design and spectral processing – are giving novel insights into a wide range of biotech drugs. Real-world applications and emerging trends in biopharmaceutical NMR are being used to help in discovery, design, and characterization of these drugs and to improve assessment of their efficacy, quality and similarity.