Bioanalysis based on nanoporous materials

Nanoporous materials possess nanometer-sized pore distribution and are widely used in biosensing. The unique properties of nanoporous materials include large surface area, good chemical, thermal and mechanical stability, very uniform pore distribution with tunable pore size, high adsorption capacity, and an ordered porous network for free diffusion of substrates and reaction products.Usage of nanoporous materials can significantly improve the analytical performance of biosensors in biomedical diagnosis and monitoring of food and environmental quality.This article reviews some major advances in bioanalysis based on nanoporous materials, including biosensing based on zeolite, mesoporous silica, mesoporous carbon, mesoporous metal and metal oxide. These nanoporous materials have shown promising applications in electrochemical biosensing, electrocatalysis, proteomics analysis and biorecognition.

► Nanoporous materials possess many advantages in their bioanalytical applications. ► Nanoporous materials significantly improve the analytical performance of biosensors. ► Recent advances in bioanalytical applications of nanoporous materials are highlighted.