Mesoporous silica-based materials for use in biosensors

There have been great advancements in the development of biosensors capable of characterizing and quantifying biomolecules. This article gives an overview of the formation, the properties and the electrochemical applications of ordered mesoporous silica-based materials in electrocatalysis, electrosorption, matrix immobilization, construction of systems for controlled release of active compounds, sensors, biosensors and immunosensors. We also present a comprehensive overview of current developments and key issues in the determination of some biological molecules with particular emphasis on the evaluation of models.

► Electrochemical applications of mesoporous materials to sensing are discussed. ► Recent advances on electrochemical sensors based on MCM and SBA are addressed. ► Mesoporous materials provide a platform for development of electrochemical biosensors.