Graphene for impedimetric biosensing

Graphene displays promising features for biosensing applications. Electrochemical impedance spectroscopy (EIS) is a very sensitive, label-free technique that is ideally suited to be coupled with a graphene platform.We discuss recent advances of graphene-based platforms for impedimetric genosensors and immunosensors. We also provide an overview on EIS and the preparation of graphene by different methods, which exhibit strong influence upon the function of the biosensor.

► Impedance spectroscopy is a powerful technique when combined with graphene surfaces. ► A biorecognition layer can attach to graphene surfaces covalently or non-covalently. ► Single-stranded DNA oligomer can be used for DNA sequence sensing or aptasensing.