Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1248561 | TrAC Trends in Analytical Chemistry | 2007 | 12 Pages |
Abstract
Metabolomics studies rely on the analysis of the multitude of small molecules (metabolites) present in a biological system. Most commonly, metabolomics is heavily supported by mass spectrometry (MS) and nuclear magnetic resonance (NMR) as parallel technologies that provide an overview of the metabolome and high-power compound elucidation. Over and above large-scale analysis, a major effort is needed for unequivocal identification of metabolites. The combination of liquid chromatography (LC)-MS and NMR is a powerful methodology for identifying metabolites. Better chemical characterization of the metabolome will undoubtedly enlarge knowledge of any biological system.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Sofia Moco, Jacques Vervoort, Sofia Moco, Raoul J. Bino, Ric C.H. De Vos, Raoul Bino,