Article ID Journal Published Year Pages File Type
1249012 TrAC Trends in Analytical Chemistry 2006 10 Pages PDF
Abstract

Advances in HPLC technology have improved capability for drug impurity profiling in terms of faster analysis time, better separations and faster method development. We review developments in monolithic columns, sub-2-μm particle columns operated at typical or high pressures, high temperature operation, new stationary phases, systematic method development, column classification techniques and selected detectors.

Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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