Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1249012 | TrAC Trends in Analytical Chemistry | 2006 | 10 Pages |
Abstract
Advances in HPLC technology have improved capability for drug impurity profiling in terms of faster analysis time, better separations and faster method development. We review developments in monolithic columns, sub-2-μm particle columns operated at typical or high pressures, high temperature operation, new stationary phases, systematic method development, column classification techniques and selected detectors.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Bernard A. Olsen, Bryan C. Castle, David P. Myers,