| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1249094 | TrAC Trends in Analytical Chemistry | 2014 | 8 Pages |
•Analytical methods in diagnosis of autism.•A metabolic profile in understanding the etiology of autism.•Determination of trace elements in autism.
Autism is a neurodevelopmental brain disorder characterized by deficiencies of language and social interaction skills, and repetitive behaviors, and is often accompanied by hyperactivity and limited attention. There are numerous theories about the specific causes of autism but they have not yet been proved. Many studies have indicated that autism has a broad multifactorial etiology, with predisposing factors including exposure to toxic chemicals, nutrient deficiencies, and genetic susceptibility. Analytical methods are important in the determination of metabolites in biological samples from autistic children for potential use as biomarkers of the disorder. Metabolic profiling helps to understand the etiology of autism and aids in the development of new treatments.
