Article ID Journal Published Year Pages File Type
1249300 TrAC Trends in Analytical Chemistry 2010 19 Pages PDF
Abstract

A common trend in food contaminants and sports doping control is towards a limited number of targeted, full-scan, accurate-mass spectrometry (MS) methods based on time-of-flight (TOF) or Fourier-transform orbital trap (Orbitrap) mass analyzers. Retrospective analysis of the full-scan datasets of signals from emerging contaminants, novel metabolites and illegal designer substances is a major step forward.We present data from recent applications of gas chromatography with TOF-MS, ultra-high-performance liquid chromatography (LC) with TOF-MS and LC-Orbitrap MS in the screening of European Commission-regulated veterinary drugs and other contaminants in foods, and World Anti-Doping Agency-prohibited substances. We discuss the potential impact of these new approaches on future developments.

Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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