Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1249505 | Vibrational Spectroscopy | 2016 | 6 Pages |
•Interactions of rifampicin chromophore with metallic surfaces.•Adsorption modulated by 2-mercaptoethanol and chloride.•Resonance Raman effect in SERS modulated by surface modifiers.
In this work the adsorption of the antibiotic rifampicin (RP) on the surface of gold (AuNP) or silver nanoparticles (AgNP) was investigated using both surface-enhanced Raman scattering (SERS) and surface-enhanced resonance Raman scattering (SERRS) spectroscopies. Such spectra were obtained in the absence and presence of the surface modifier 2-mercaptoethanol (ME) using excitations by laser radiations of 532, 632.8 and 1064 nm wavelengths. The use of different conditions under the presence of ME led to changes in the spectral pattern ascribed to the influence of resonance Raman (RR) effect and distinct chemical interactions of RP with the metallic surfaces. The sensibility of the chromophoric moiety, i.e. a