Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1250934 | Arabian Journal of Chemistry | 2014 | 8 Pages |
Abstract
The compounds styryl 1,3,4-thiadiazoles were prepared adopting one and two step methodologies to optimize the yield of the products. The two-step methodology via benzohydrazide followed by treatment with Lawesson’s reagent in the presence of Propylphosphonic anhydride and triethylamine produced styryl 1,3,4-thiadiazoles in excellent yields. The olefin moiety in these compounds is utilized to develop pyrazole and isoxazole rings by 1,3-dipolar cycloaddition methodology followed by oxidation.
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Authors
Mallikarjuna Reddy Guda, Sravya Gundala, Venkatapuram Padmavathi, Adivireddy Padmaja,