Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1251569 | Chemical Research in Chinese Universities | 2008 | 6 Pages |
Abstract
A complete study of the asymmetric addition of phenylacetylene to ketones catalyzed by Schiff-base amino alcohol-Zn complex is reported in this article. The Schiff-base amino alcohols were easily prepared from amino acids in three steps. When the amount of ligand was 1%(molar fraction), an e.e. value up to 94% was obtained. A series of practical chiral ligands were applied in the enantioselective addition of phenylacetylene to ketones without adding another stronger Lewis acid except zinc.
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Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Chao CHEN, Liang HONG, Quan WANG, Bang-zhi ZHANG, Rui WANG,