| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1252673 | Chemistry and Physics of Lipids | 2006 | 7 Pages |
Abstract
Complete 1H and 13C resonance assignments were made for a new type of 3β,7β-dihydroxy-5-cholen-24-oic acid doubly conjugated with sulfuric acid at C-3 and N-acetylglucosamine at C-7 and its glycine- and taurine-amidated triple-conjugates by the combined use of several homonuclear and heteronuclear shift-correlated 2D NMR techniques. The effects of sulfation at C-3, N-acetylglucosaminidation at C-7, and aminoacyl amidation at C-24 on the 1H and 13C chemical shifts and signal multiplicity were clarified. The shielding data serving to characterize each of the bile acid multi-conjugates are also discussed.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Genta Kakiyama, Shoujiro Ogawa, Takashi Iida, Yasuo Fujimoto, Kumiko Mushiake, Takaaki Goto, Nariyasu Mano, Junichi Goto, Toshio Nambara,