Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1252789 | Arabian Journal of Chemistry | 2014 | 8 Pages |
Abstract
Treatment of cyanoacetanilide derivative 1 with tetracyanoethylene (2) in dioxane/triethylamine furnished 2-pyridone derivative 6. Aminopyridine 9 was obtained by cyclization of compound 1 with ketene dithioacetal 7/EtONa. Cyclocondensation of 1 with malononitrile and/or acetylacetone (1:1 M ratio) gave pyridine derivatives 11 and 13. Ternary condensation of compound 1, aliphatic aldehydes and malononitrile (1:1:1 M ratio) yielded the 2-pyridones 20a and b. Bipyridines 22a–c were prepared by refluxing of compound 21 with active methylene reagents. Cyclization of chromene derivatives 24 and 28 with malononitrile produced the novel chromeno[3,4-c]pyridine 26 and pyrano[3′,2′:6,7]chromeno[3,4-c]pyridine 29.
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Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Yousry A. Ammar, Mohamed S.A. El-Gaby, Mohamed A. Salem,