| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1259863 | Current Opinion in Chemical Biology | 2010 | 7 Pages |
Abstract
Time-dependent single-molecule spectroscopy allows the direct observation of molecular processes in real time, capturing transient and stochastic events that cannot be detected using conventional ensemble-averaged methods. It offers a promising approach to uncovering the physical and chemical transformations underlying cellular responses. Recent advances in the probe development, specific labeling strategies, and spectroscopy instrumentation suggest the feasibility of monitoring a single molecular machine's actions inside a living cell.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Haw Yang,