Prevalence of microbial pathogens in blood cultures: an etiological and histopathological study

Performance of BACTEC 9120 blood culture system was compared with the conventional (manual) broth method in detecting blood cultures of 500 patients suffering from various diseases. The BACTEC system proved to be superior in both yield and speed of detection. Four species of yeasts belonging to 2 genera and 13 species of bacteria belonging to 12 genera were recovered from the patient's blood cultures. The study confirmed the serious role of yeasts present in patient blood, and highlighted the serious pathological effect of their secondary metabolites, including clinical symptoms ending with death, besides the changes in the histological pattern in the internal organs, as liver, kidney and spleen using mice as an experimental animal model.