| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1263949 | Organic Electronics | 2013 | 8 Pages |
We describe a potentiometric sensor based on Electrolyte-Gated Organic Field-Effect Transistor (EGOFET) for “in vitro” detection of dopamine. The sensing element of this device resides at the Au gate–aqueous solution interface by means of a self-assembled monolayer (SAM) composed by cysteamine and 4-formylphenyl boronic acid. The covalent and selective adsorption of dopamine induces a surface dipole potential which shifts the electrode work function and modulates the double layer capacitance. As a result, our device is capable to detect dopamine up to pico-molar concentration showing higher sensitivity with respect to other approaches. For this reason the interface engineering of our EGOFET gate is a promising route for diagnostic applications.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► We describe a new EGOFET capable to sense dopamine. ► Interface engineering of gate electrode merged with EGOFET transduction provide a powerful sensing approach. ► EGOFET sensitivity is effective down to pico-molar concentration of dopamine.
