Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1269611 | Ultrasonics Sonochemistry | 2015 | 7 Pages |
Abstract
Phenol derived O-glycosides were synthesized using a direct and convenient O-glycosidation, starting from acetylated sugars in the presence of FeCl3, an inexpensive, mild and benign Lewis acid catalyst. The reactions were carried out under both conventional and ultrasonic irradiation conditions. In general, improvement in rates and yields were observed when reactions were carried out under sonication compared with conventional conditions leading to the corresponding β-O-glycosides as the major anomer. Post-synthetic transformations of iodophenol intermediates led to new resveratrol O-glycoside analogs in good overall yields.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Hamid Marzag, Guillaume Robert, Maeva Dufies, Khalid Bougrin, Patrick Auberger, Rachid Benhida,