Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1270170 | Ultrasonics Sonochemistry | 2012 | 6 Pages |
In this research, rapid and efficient preparation of 2,2-dichloro-1,3-diarylaziridines through the reaction of Schiff base compounds with dichlorocarbene yielded in situ from chloroform and sodium hydroxide without any phase transfer catalyst under ultrasonic irradiation is described. The advantages of this reaction are very short reaction times, excellent product yields, simplicity of the method and high purity of products.
Graphical abstractIn this research, rapid and efficient preparation of 2,2-dichloro-1,3-diarylaziridines through the reaction of Schiff base compounds with dichlorocarbene yielded in situ from chloroform and sodium hydroxide without any phase transfer catalyst under ultrasonic irradiation is described. The advantages of this reaction are very short reaction times, excellent product yields, simplicity of the method and high purity of products.Figure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Ultrasonic irradiation catalyzed synthesis of gem-dichloroaziridines. ► Any PTC was needed for this reaction under ultrasonic conditions. ► Products were obtained in excellent yields and short reaction times. ► Simplicity of the method and high purity of products.