| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1299044 | Coordination Chemistry Reviews | 2016 | 25 Pages |
•Synthesis and chemistry of ferrocenyl-nucleobases are reviewed.•Biological applications of ferrocenyl-nucleobases are discussed.•The relevance of ferrocenyl-nucleobases for self-assembly materials is shown.
Ferrocenyl-nucleobases are an increasingly important class of complexes with possible applications in biology, pharmacy and material sciences. This review focuses on synthetic methods for ferrocenyl-nucleobases and on the chemical transformations of these compounds. Utilization of ferrocenyl-nucleobases for self-assembly material preparation and as building blocks for XNA synthesis and anticancer and antibacterial agents is also discussed herein. This review shows that the combination of the redox-active biologically artificial ferrocenyl moiety and genetically essential nucleobases leads to conjugates that retain their electrochemical and self-pairing properties. These properties make ferrocenyl-nucleobases attractive objects for further studies and for applications across the entire spectrum of physico-chemical and engineering sciences.
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