| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1299119 | Coordination Chemistry Reviews | 2012 | 27 Pages |
The coordination behaviour of ligands containing the vitamin B6 vitamers [pyridoxal (PL), pyridoxine (PN), pyridoxamine (PM) and their 5′-phosphates] is reviewed in the light of the structural information derived from X-ray studies. The review includes the complexes of the simple vitamers themselves or simple derivatives thereof; those of the Schiff bases resulting from their condensation with each other or with amino acids or other amino derivatives; and the metal compounds formed by hydrazones that contain the PL moiety. Taken together, these ligands exhibit a wide variety of coordination possibilities, the vitamer moiety usually playing a significant role. The biological relevance and therapeutic potential of some of these compounds are also reviewed.
Graphical abstractFigure optionsDownload full-size imageDownload high-quality image (85 K)Download as PowerPoint slideHighlights► Coordination chemistry of vitamin B6 vitamers (PN, PM and PL). ► PLPM Schiff bases as ligands. ► Exploring the coordination behaviour of PLaa derivatives. ► Metal complexes containing non-reduced and reduced ligands derived from PL and mono-, di- and triamines. ► PL hydrazone complexes.
