Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1299347 | Coordination Chemistry Reviews | 2009 | 20 Pages |
Abstract
1,4,7,10-Tetraazacyclododecane-N,N′,N″,N′″-tetraacetic acid (DOTA) is one of the preeminent carriers of metal-based radiopharmaceutics and imaging contrast agents. This review focuses on the coordination chemistry of metal–DOTA complexes with a view to addressing the variability of structures obtained and gaining insight into its diversity. Correlations on thermodynamic stabilities with structural motifs are reported. Observed trends are analyzed with a view to providing a structure–stability relationship.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Nerissa Viola-Villegas, Robert P. Doyle,