Ephedrine derivatives, extraordinary tools for the study of stereogenic centers in tetra- to heptacoordinated complexes

We have been investigating the synthesis of diverse ephedrine derivatives, as polyfunctional ligands, heterocyclic compounds, and metal and metalloid complexes. In this review, we present a brief discussion of our experience and from other research groups concerning the creation of stereogenic centers, different from carbon, in diverse ephedrine based molecules.