Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1300238 | Coordination Chemistry Reviews | 2010 | 21 Pages |
Abstract
N-alkylation of macrocyclic amines has a significant impact on their properties as ligands for metal ions. This article examines the development of the coordination chemistry of N-alkylated cyclam ligands from its inception in 1973 with the first report of tetramethylcyclam. Emphasis is on: (1) the stereochemistry of metal complexation, including the effects of inclusion of functional groups in one or two of the N-alkyl groups; (2) the effect of N-alkylation on the metal–donor interaction; (3) the ability of tertiary amine ligands to stabilize complexes of metal ions in unusual oxidation states.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
E. Kent Barefield,