Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1301104 | Coordination Chemistry Reviews | 2011 | 19 Pages |
Abstract
⺠Lipophilicity of a coordination complex is predictable based on the log P of the AL. ⺠MIL-101 shows remarkable drug loading capacity, 140% (w/w) of drug/carrier. ⺠CPs show exceptional performance over the adsorption-storage-delivery cycle for NO. ⺠In animal studies, no significant toxic effects were observed for MIL(Fe) NCPs. ⺠Anti-HIV activities of AZT-TP loaded NCPs were proven.
Keywords
MILCuSAPIESI-MSASPADMETGRASSBFSASDSCPPiBNMESNSAIDSMOPSXRPDSEDDSBIXDaunomycinFDAMCPSNanoscale coordination polymersDDSsNCPsCPTPVPDLSBDCPBScpsDOXDFTMOFsDAUElectrospray Ionization Mass SpectrometryTerephthalic acidgenerally recognized as safeDrug deliveryabsorption, distribution, metabolism, excretion, and toxicityNonsteroidal anti-inflammatory drugsPharmaceuticalSBUCNSDoxorubicinBCsFood and Drug AdministrationBBBBlood–brain barrierSupramolecularSelf-emulsifying drug delivery systembiopharmaceutics classification systemcentral nervous systemDrug delivery systemsDOSYMetal-Organic FrameworksIbuprofenLDHAncillary ligandIbuSimulated body fluidPhosphate-buffered salineSEMActive Pharmaceutical Ingredientscanning electron microscopeNanoscaleDensity functional theoryNew molecular entitiesNitric oxideCoordinationLayered double hydroxideSecondary building unitsDynamic Light Scatteringpolyethylene glycolpolyvinyl pyrrolidoneCoordination polymersPEGcamptothecin
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Zhenbo Ma, Brian Moulton,