Recent advances in arylene ethynylene folding systems: Toward functioning

Well-defined 3-dimensional architectures constitute the indispensable structural basis of the versatile, mind-boggling functions of biological macromolecules, such as proteins and nucleic acids. In the past few decades, diversified synthetic systems have been designed to mimic these biological entities in their capability of adopting such specific, higher order structures. The relevant research field presents one of the most rapidly developing areas related to supramolecular chemistry. The current contribution will focus on the most recent progress related to foldamers consisting of arylene ethynylene building blocks. Some of the work features developing novel functions based on previously established arylene ethynylene folding systems, and others have designed and synthesized new arylene ethynylene foldable structures that aim to realize previously uncharted properties.