Self-assembled pentagonal bipyramidal and skew trapezoidal organotin(IV) complexes of substituted benzoic acids: Their antibacterial, antifungal, cytotoxic, insecticidal and urease inhibition activities

Fourteen di- and triorganotin(IV) derivatives with pentagonal bipyramidal and skew trapezoidal geometries have been synthesized and characterized. Dimethylstannyl bis[3-amino-4-chlorophenylcarboxylate] (1), bis[3-amino-4-chlorophenylcarboxylato] tetraethyldistannoxane] (2) and bis[3,5-dinitro-4-chlorophenylcarboxylato] tetra-n-butyldistannoxane (10) are dinuclear and tetranuclear complexes of bidentate ligands. The crystal structure of (1) is dimeric in which each Sn atom is seven coordinated. Study of weak intramolecular Sn⋯O interactions is very important to decide geometry around tin. Furthermore, it has been investigated that these compounds exhibit fairly good antibacterial, antifungal, cytotoxic, insecticidal and antiurease activities.

Graphical abstractA series of new mononuclear, dinuclear and tetranuclear organotin(IV) derivatives of substituted benzoic acids have been synthesized and structurally characterized by various spectroscopic techniques and X-ray crystallography. The antibacterial, antifungal, cytotoxic, insecticidal and urease inhibition activities of these compounds have also been studied.Figure optionsDownload full-size imageDownload as PowerPoint slideResearch highlights► Synthesis of pentagonal bipyramidal and skew trapezoidal organotin(IV) complexes. ► Weaker interactions affect the structure of these compounds in solid state. ► These interactions have been studied in solution state by multinuclear NMR spectroscopy. ► The compounds have shown fairly good biological activities.