| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1308909 | Inorganica Chimica Acta | 2011 | 7 Pages |
Gold–thioguanine nanoconjugates (AuNP–TG) of size 3–4 nm were synthesized and the ratio between gold and 6-thioguanine (TG) was estimated as ∼1:1.5 using a cyanide digestion method and confirmed by flame atomic absorption spectroscopic analysis. AuNP–TG constructs showed high in vitro stability under different pH conditions and biologically relevant solutions for a period of 24 h. Reaction of AuNP–TG with europium or platinum salts resulted in the formation of organized self-assembled metallo-networks.
Graphical abstractGold-thioguaninenanoconjugates (AuNP-TG) of average size 3.5 nm have been synthesized and characterized. The utility of AuNP-TG asmetallo-ligands has been established by complexing with Europium and Platinum salts. With europium, a novel hexagonal type metallo-network was formed and with platinum AuNP-TG forms a linear assembly.Figure optionsDownload full-size imageDownload as PowerPoint slideResearch highlights► AuNP-TG conjugates of average size 3.5 nm have been synthesized. ► AuNP–TG conjugates are highly stable in biologically relevant conditions. ► AuNP–TG conjugates serve as metallo-ligands by complexing with Eu/Pt salts. ► With Europium, AuNP-TG forms a novel hexagonal metallo-network. ► With Platinum, AuNP-TG forms a linear self-assembly of nanoparticles.
