Structural, morphological and biological investigations of some transition metal-5-Fluorouracil-amino acid mixed ligand complexes

MAB (where M = Ni(II)/Cu(II)/Zn(II); A = 5-FU; B = phe) type complexes (1a-1c) were isolated in their solid state and characterized by various physico-chemical, spectral, TG/DTA and XRD/SEM techniques. Additionally, the stability constants and thermodynamic parameters (Δ‡G, Δ‡H and Δ‡S) of various binary and mixed ligand complexes in solution state of Cu(II) with 5-Fluorouracil (5-FU), glycine(gly), l-alanine(ala), l-valine(val) and l-phenylalanine(phe) were investigated.