Article ID Journal Published Year Pages File Type
1310290 Inorganica Chimica Acta 2008 5 Pages PDF
Abstract
Hydroxymandelate synthase (HMS) will bind NTBC, a herbicide/therapeutic that acts by the inhibition of hydroxyphenylpyruvate dioxygenase (HPPD). This occurs despite key residues in the active site of HMS differing from those in HPPD. In addition, the observed kinetic steps for association of NTBC to HMS are similar to those previously observed with HPPD.
Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
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