Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1312876 | Inorganica Chimica Acta | 2006 | 10 Pages |
Abstract
As part of an investigation on the coordination ability of peptides, the dipeptide glycylalanine (H-Gly-Ala-OH), tripeptide glycylalanylalanine (H-Gly-Ala-Ala-OH) and their Au(III)-complexes have been characterized structurally. The quantum chemical calculations and linear-dichroic infrared (IR-LD) spectroscopy predict structures of the compound studied, which are compared with a single crystal X-ray diffraction of H-Gly-Ala-OH. The coordination processes with Au(III) are supported by data for 1H NMR, ESI-MS, HPLC-MS-MS, TGV and DSC methods. The [Au(Gly-Ala)Hâ1Cl] and [Au(Gly-Ala-Ala)Hâ2] · 2H2O complexes are formed via -NH2, Nâamide/s and CO2- groups of the peptides. One Clâ ion is attached to the metal center as terminal ligand in the first complex. In both cases a near to square-planar geometry of the chromophors AuN2OCl and AuN3O is yielded.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Ts. Kolev, B.B. Koleva, S.Y. Zareva, M. Spiteller,