Article ID Journal Published Year Pages File Type
1312876 Inorganica Chimica Acta 2006 10 Pages PDF
Abstract
As part of an investigation on the coordination ability of peptides, the dipeptide glycylalanine (H-Gly-Ala-OH), tripeptide glycylalanylalanine (H-Gly-Ala-Ala-OH) and their Au(III)-complexes have been characterized structurally. The quantum chemical calculations and linear-dichroic infrared (IR-LD) spectroscopy predict structures of the compound studied, which are compared with a single crystal X-ray diffraction of H-Gly-Ala-OH. The coordination processes with Au(III) are supported by data for 1H NMR, ESI-MS, HPLC-MS-MS, TGV and DSC methods. The [Au(Gly-Ala)H−1Cl] and [Au(Gly-Ala-Ala)H−2] · 2H2O complexes are formed via -NH2, N−amide/s and CO2- groups of the peptides. One Cl− ion is attached to the metal center as terminal ligand in the first complex. In both cases a near to square-planar geometry of the chromophors AuN2OCl and AuN3O is yielded.
Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
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