Article ID Journal Published Year Pages File Type
1313044 Inorganica Chimica Acta 2006 6 Pages PDF
Abstract
The chemical reactivity of mononucleobase cations: SP-4-2-[PtCl(9-EtGua)(NH3)(quinoline)]+ and trans-[PtCl(9-EtGua)(pyridine)2]+ with the model compounds 5′-guanosine monophosphate and N-Acetylmethionine was studied by 1H NMR spectroscopy. Reactivity studies were extended to the biologically relevant protein Ubiquitin. The differences obtained between model and protein substrates are compared and the potential biological implications are discussed.
Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
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