Synthetic utility of 2,3,3,3-tetrafluoroprop-1-ene (HFO-1234yf)

•Realization of addition–elimination reactions of 2,3,3,3-tetrafluoroprop-1-ene with alkoxides in good to excellent yields.•Ready chromatographic isolation of the corresponding products.•Facile derivatization of acetals of 1-bromo-3,3,3-trifluoroacetone.

2,3,3,3-Tetrafluoroprop-1-ene, known as the environmentally benign fluorinated olefin recently employed for the car air-conditioning system, was proved to follow the addition–elimination sequence at its C2 position by the reaction of a variety of alkoxides, forming CF3-containing vinyl ethers in excellent yields.

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