Functionalized S-perfluorinated sulfoximines: Preparation and evaluation in catalytic processes

•Preparation of functionalized perfluoroalkylated sulfoximines.•Coupling reaction under copper catalysis.•Microwave activation.•Catalysis and organocatalysis.

N-substituted S-perfluoroalkylated sulfoximines were synthesized from the NH sulfoximines either by a copper coupling reaction with aryl halides or by a reaction with electrophilic substrates. The procedure allowed the preparation of N,N′-bridged bis sulfoximines and of thioureas. The potential of these new sulfoximines was evaluated in different catalytic processes.

Graphical abstractN-substituted S-perfluoroalkylated sulfoximines were synthesized from the NH sulfoximines either by a copper coupling reaction with aryl halides or by a reaction with electrophilic substrates. The procedure allowed the preparation of N,N′-bridged bis sulfoximines and of thioureas. The potential of these new sulfoximines was evaluated in different catalytic processes.Figure optionsDownload full-size imageDownload as PowerPoint slide