Article ID Journal Published Year Pages File Type
1313859 Journal of Fluorine Chemistry 2013 7 Pages PDF
Abstract

•A new method for the copper-mediated trifluoromethylation of 5-iodotriazole was reported.•The (trifluoromethyl)trimethylsilane was used as trifluoromethylating reagent.•The addition of silver carbonate is essential for efficient conversion.

A novel and mild method for copper-mediated trifluoromethylation of 5-iodotriazole using (trifluoromethyl)trimethylsilane (Me3SiCF3) as trifluoromethylating reagent with the assistance of Ag2CO3 was developed.

Graphical abstractA novel and mild method for the copper-mediated trifluoromethylation of 5-iodotriazole using (trifluoromethyl)trimethylsilane as trifluoromethylating reagent with the assistance of Ag2CO3 was developed.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
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