Article ID Journal Published Year Pages File Type
1313896 Journal of Fluorine Chemistry 2012 38 Pages PDF
Abstract

The synthesis of fluorinated highly modified nucleoside analogues—carbanucleosides, aromatic nucleosides, acyclic nucleosides and related derivatives are reviewed.

Graphical abstractThe synthesis of fluorinated highly modified nucleoside analogues are reviewed.Figure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Highly modified fluorinated analogues of nucleosides are overviewed. ► Synthesis and design of fluorinated carbocyclic nucleosides. ► Aromatic nucleoside isosteres as probes of noncovalent bonding in DNA. ► Fluorinated acyclic nucleosides as antiviral agents and tracers for PET.

Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
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