| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1313909 | Journal of Fluorine Chemistry | 2012 | 6 Pages |
Abstract
2-Chloro-1,1,1,2-tetrafluoroethane 1 (HCFC-124) obtained as one of the major byproducts of tetrafluoroethylene synthesis were successfully employed for the stereodivergent construction of tetrafluorinated enamides 4 just by selection of a base for affecting the removal of HCl.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Convenient reaction of HCFC-124 with aromatic imines protected by Boc or Ts groups on nitrogen. ► Smooth conversion of aromatic groups in the above products to the methyl ester in two steps. ► Stereodivergent construction of fluorinated enamides just by selection of a base.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Shin Ota, Tomoko Kawasaki-Takasuka, Takashi Yamazaki, Toshio Kubota,