Article ID Journal Published Year Pages File Type
1314042 Journal of Fluorine Chemistry 2012 8 Pages PDF
Abstract

Reactions of 6-(tri- and 6-(difluoromethyl))comanic acids with aniline, o-phenylenediamine and o-aminophenol were investigated. RF-containing derivatives of 4-pyridones, benzodiazepines and quinoxalinones were synthesized. Electrophilic properties of 6-(trifluoromethyl)comanic acid were evaluated.

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Reactions of 6-(tri- and 6-(difluoromethyl))comanic acids with aniline and its 2-substituted derivatives were investigated. ► RF-containing 4-pyridones, benzodiazepines and quinoxalinones were synthesized. ► Electrophilic properties of 6-CF3-comanic acid were evaluated.

Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
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