Insight into “entrainment” in SRN1 reactions of 2,2-dichloro-1,1,1-trifluoroethane(HCFC-123) with thiolates initiated by Na2S2O4

•Entrainment reaction.•Indirect SRN1 reaction.•Cleavage of unactivated CCl bond.

An interesting entrainment process in SRN1 reactions of 2,2-dichloro-1,1,1-trifluoroethane (HCFC-123) with thiolates were studied by experiments and DFT calculations. The radical-anion intermediate, generated from coupling of the fluorinated radical with the thiolate was considered as the key intermediate in this reaction.

Graphical abstractEntrainment process was found in the SRN1 reaction of HCFC-123 with thiolates initiated by catalytic amount Na2S2O4.Figure optionsDownload full-size imageDownload as PowerPoint slide