| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1314104 | Journal of Fluorine Chemistry | 2012 | 4 Pages |
Trifluoromethanesulfanylamides constitute a family of easily available reagents which could provide efficient ways to perform electrophilic trifluoromethanesulfanylation. In particular they are able to react with electron-rich aromatic compounds, more particularly with indoles, to yield expected CF3S-subtituted molecules with good results.
Graphical abstractElectron-rich aromatic compounds, in particular indoles, were trifluoromethanesulfanylated by trifluoromethanesulfanylamides under acidic activations.Figure optionsDownload full-size imageDownload as PowerPoint slideResearch highlights► New reagents for electrophilic trifluoromethanesulfanylation. ► Electrophilic aromatic trifluoromethanesulfanylation of electron-rich compounds. ► Indoles are good substrates for this reaction.
