| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1314214 | Journal of Fluorine Chemistry | 2010 | 5 Pages |
Abstract
A simple, inexpensive, environmentally friendly and efficient route for the synthesis of benzimidazole and formamidine derivatives by the reaction of O-phenylenediamines or amines with orthoesters using hexafluoroisopropanol as a solvent/catalyst is described.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideResearch highlights▶ Synthesis of benzimidazole and formamidine derivatives. ▶ Synthesis of unsymmetrical formamidine derivatives. ▶ Using hexafluoroisopropanol as a solvent. ▶ A new medium for activation of orthoesters. ▶ Ease of product isolation/purification by non-aqueous work-up.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Samad Khaksar, Akbar Heydari, Mahmood Tajbakhsh, Seyed Mohammad Vahdat,