A recyclable fluoroalkylated 1,4-disubstituted [1,2,3]-triazole organocatalyst for aldol condensation of aldehydes and ketones

A new fluoroalkylated 1,4-disubstituted [1,2,3]-triazole was prepared and acted as an organocatalyst for aldol condensation of different ketones with various aldehydes. Aldol condensation proceeded efficiently in the presence of catalytic amount of fluoroalkylated [1,2,3]-triazole. The catalyst could be easily recovered by fluorous solid-phase extraction with excellent purity and reused for three runs with slightly decrease in its activity.

Graphical abstractFluoroalkylated 1,4-disubstituted [1,2,3]-triazole catalyzed aldol condensation of different ketones with different aldehydes to give various α,β-unsaturated ketones in good yields.Figure optionsDownload full-size imageDownload as PowerPoint slide