Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1314403 | Journal of Fluorine Chemistry | 2011 | 4 Pages |
The system hexafluoroisopropanol/ethyl diazoacetate/Cu(OTf)2 is efficient for the cyclopropanation reaction. The process is experimentally simple, and efficient with various olefins in particular terminal, disubstituted double bonds.
Graphical abstractThe system hexafluoroisopropanol/ethyl diazoacetate/Cu(OTf)2 is efficient for the cyclopropanation reaction. The process is very easy to realize, and efficient with various olefins in particular terminal, disubstituted double bonds.Figure optionsDownload full-size imageDownload as PowerPoint slideHighlights► The system hexafluoroisopropanol/ethyl diazoacetate/Cu(OTf)2 is efficient for the cyclopropanation reaction. ► The advantages of these new solvent conditions is the lack of specific experimental requirements. ► The process is compatible with various olefins in particular terminal, disubstituted, double bonds.